1) In December 2008, the Swedish Medical Products Agency completed a safety investigation of Propecia. They concluded that the use of Propecia might result in irreversible sexual side-effects. The Agency’s updated safety information now includes “persistence of erectile dysfunction after discontinuation of treatment with Propecia” as a possible adverse reaction to the drug.
2) In December 2009, the Medicines and Healthcare products Regulatory Agency in the UK announced new drug safety data on finasteride. After carefully reviewing the results of several controlled studies, the agency wrote “an increased risk of male breast cancer associated with finasteride use cannot be excluded.” On the basis of this information, it was recommended that a warning should be included in the product information for all medicines containing finasteride mentioning the possible risk of breast cancer. To read the full article – click here
3) This 2006 research paper, published in the CNS Drug Reviews medical journal, raises the possibility that finasteride can cross blood-brain barrier (BBB) and interfere with neurosteroids. This could have a noticeable impact on brain function. To read the full article – click here
4) The majority of available clinical data on finasteride comes from various 5-year studies. The long-term implications of finasteride consumption remain unknown. Because finasteride treatment must be continued indefinitely, this is an important consideration.
5) Merck’s clinical data reveals that the side-effects of finasteride include impotence (1.1% to 18.5%), abnormal ejaculation (7.2%), decreased ejaculatory volume (0.9% to 2.8%), abnormal sexual function (2.5%), gynecomastia (2.2%), erectile dysfunction (1.3%), ejaculation disorder (1.2%) and testicular pain.
We understand that finasteride is a very popular treatment option for many customers. Nonetheless, safety is our foremost concern. Finasteride works by inhibiting 5-alpha-reductase, the androgen responsible for converting testosterone into dihydrotestosterone (DHT). Unfortunately dihydrotestosterone is not only found in hair follicles. It is also synthesized in the testes, prostate and adrenal glands. Thus, the suppression of DHT may have a negative impact many other important biological processes.
We feel it is imperative for customers to know exactly what they are ingesting when they take prescription medication. While it is true that finasteride has a respectable safety profile in comparison to other treatments, the risks still greatly outweigh any potential benefits.
Luckily, there are other options for the treatment of pattern hair loss.
TRX2® Molecular Supplement for Hair capsules are completely free of side effects. Used exclusively or, to maximise effects, in combination with 5% minoxidil, our product has been proven to slow the progression of hair loss and revitalise miniaturised hair follicles. More safe and affordable than any alternative, our unique line of TRX2® treatments is changing the way customers approach their hair loss. Experience our commitment to innovation, quality and results – try TRX2® today !
Question: Dr. Thomas Whitfield. Thank you very much for the E-Course regarding hair biology. The information is useful, however I still have a few questions.
Do you really think that finasteride is a good preventive treatment? Would you recommend that an 18 year old with all of his hair start finasteride treatment to prevent the progression of male pattern baldness?
It seems to me that this could be unhealthy. Thanks, TIA
Answer: Thanks for your question – this is a very good point you have.
As a matter of fact, at TRX2® we highly recommend NOT using finasteride. In short, the long-term risks of using this medication are impossible to ascertain. From a scientific perspective, a number of studies have been carried out that really call into question the safety of finasteride. Although the data might not be absolutely definitive, we don’t believe anyone should take unnecessary risks with regard to their health.
Hope this helps & please stay tuned!
Send your questions to [email protected]
Thomas F.A. Whitfield, DPhil, is an internationally recognized expert on potassium ion channels, former scientist of the University of Oxford’s Department of Biochemistry and member of TRX2®’s Scientific Advisory Board.