5α-Reductase Inhibitor Treatment for Androgenetic Alopecia
After conducting a substantial amount of research into this area, we highly recommend replacing  5α-Reductase inhibitors with a safe and natural alternative. This suggestion comes after careful consideration of several important factors:
1) In December 2009, the Medicines and Healthcare products Regulatory Agency in the UK announced new drug safety data on  5α-Reductase inhibitors. After carefully reviewing the results of several controlled studies, the agency wrote, “an increased risk of male breast cancer associated with  5α-Reductase inhibitors use cannot be excluded.” On the basis of this information, it was recommended that a warning should be included in the product information for all medicines containing 5α-Reductase inhibitors mentioning the possible risk of breast cancer. To read the full article – click here
2) A 2006 research paper, published in the CNS Drug Reviews medical journal, raises the possibility that5α-Reductase inhibitors can cross the blood-brain barrier (BBB) and interfere with neurosteroids. This could have a noticeable impact on brain function. To read the full article – click here
3) The majority of available clinical data on  5α-Reductase inhibitors comes from various 5-year studies. The long-term implications of  5α-Reductase inhibitors consumption remain unknown. Because  5α-Reductase inhibitor treatment must be continued indefinitely, this is an important consideration.
4) Merck’s clinical data reveals that the side effects of  5α-Reductase inhibitors include impotence (1.1% to 18.5%), abnormal ejaculation (7.2%), decreased ejaculatory volume (0.9% to 2.8%), abnormal sexual function (2.5%), gynecomastia (2.2%), erectile dysfunction (1.3%), ejaculation disorder (1.2%) and testicular pain.
We understand that  5α-Reductase inhibitors are a very popular treatment option for many people. Nonetheless, safety is our foremost concern.  5α-Reductase inhibitors work by inhibiting 5-alpha-reductase, the androgen responsible for converting testosterone into dihydrotestosterone (DHT). Unfortunately, dihydrotestosterone is not only found in hair follicles. It is also synthesised in the testes, prostate and adrenal glands. Thus, the suppression of DHT may have a negative impact on many other important biological processes.
We feel it is imperative for customers to know exactly what they are ingesting when they take prescription medication. While it is true that  5α-Reductase inhibitors have a respectable safety profile in comparison to other treatments, the risks still greatly outweigh any potential benefits.
Luckily, there are other options for the treatment of pattern hair loss.
TRX2® Molecular Hair Regimen is completely free of side effects. Our products have been proven to slow the progression of hair loss and revitalize miniaturized hair follicles. More safe and affordable than any alternative, our unique line of TRX2® treatments is changing the way customers approach their hair loss. Experience our commitment to innovation, quality and results with TRX2®.